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Analytical and pharmacological studies on Mahonia aquifolium.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Galle, K. Müller-Jakic, B. Proebstle, Albrecht Jurčić, Kristina Bladt, Sabine Wagner, Hildebert |
| Copyright Year | 1994 |
| Abstract | Alcoholic extracts of the antipsoriatic Mahonia aquifolium drug which were analysed for their qualitative and quantitative alkaloid content, showed an in vitro inhibiting effect on cyclo-oxygenase (CO) of sheep seminal vesicles and 5-lipoxygenase (5-LO) of porcine leucocytes. The same extracts exhibited also immunostimulating activities in two phagocytosis assays. In contrast the major alkaloids of Mahonia aquifolium extracts berberine, palmatine, magnoflorine and jatrorrhizine were found to be inactive at all in both antiinflammatory assays, suggesting a different mechanism of action for the alkaloids or further not yet detected compounds in the extract. |
| Starting Page | 59 |
| Ending Page | 62 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0944-7113(11)80024-3 |
| PubMed reference number | 23195817 |
| Journal | Medline |
| Volume Number | 1 |
| Issue Number | 1 |
| Alternate Webpage(s) | https://pdfs.nutramedix.ec/Barberry%20-%20Immunomodulating.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/S0944-7113%2811%2980024-3 |
| Journal | Phytomedicine : international journal of phytotherapy and phytopharmacology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |