NDLI: Relationship between eNOS gene polymorphism and cerebral infarction of young and middle-aged Chinese Han population.

Please wait, while we are loading the content...

Relationship between eNOS gene polymorphism and cerebral infarction of young and middle-aged Chinese Han population.

Content Provider	Semantic Scholar
Author	Hu, Huabin Huang, Yanhui Jiang, Ling Yangn, M. J. Xu, Shang Yan Wang, Yi Hu, Zhi Ping
Copyright Year	2014
Abstract	PURPOSE To discuss the relationship between the acute cerebral infarction of differently aged population and the variable number tandem repeat polymorphism of endothelial nitric oxide synthase (eNOS) gene. METHODS The genotypes of 129 acute cerebral infarction patients and 100 healthy control subjects were determined by PCR and polyacrylamide gel electrophoresis (PAGE). RESULTS In the patient group, the frequency of allelic gene a was higher than that in the control group (13.56 % vs 3 %, p < 0.01), and the frequencies of the patients followed the descending order from young through middle-aged to elderly (42.31 % vs 17.2 % vs 5.8 %). The frequencies of the young, middle-aged and elderly population in the control group differed significantly (5.55 % vs 2.94 % vs 2.63 %), and those of the young and middle-aged population in the two groups also differed statistically significantly. CONCLUSION The ab genotype of eNOS 4th intron is correlated with the acute cerebral infarction of young and middle-aged Chinese Han population that may involve allelic gene a as an independent risk factor (Tab. 3, Fig. 3, Ref. 13).
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.elis.sk/download_file.php?product_id=4058&session_id=717afa2ce0ef9f908ba879e6ff225f0f
PubMed reference number	25428540v1
Volume Number	115
Issue Number	11
Journal	Bratislavske lekarske listy
Language	English
Access Restriction	Open
Subject Keyword	Alleles Cerebral Infarction Common Variable Immunodeficiency Gel Electrophoresis (lab technique) NOS3 gene NOS3 protein, human Nitric Oxide Synthase Patients Polyacrylamide Gel Electrophoresis Tandem Repeat Sequences polyacrylamide gels
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in