NDLI: Evaluation of the effects of stress on the sympathetic nervous system and hypothalamic-pituitary-adrenal axis in cats with feline interstitial cystitis.

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Evaluation of the effects of stress on the sympathetic nervous system and hypothalamic-pituitary-adrenal axis in cats with feline interstitial cystitis.

Content Provider	Semantic Scholar
Author	Westropp, Jodi L.
Copyright Year	2005
Abstract	We systematically identified and evaluated various animal models that have been studied to help identify the underlying mechanisms of and possible treatment options for interstitial cystitis. Models of interstitial cystitis published between 1983 and 2001 were obtained by searching MEDLINE and other Internet databases using cystitis and model as the primary key words. Models with characteristics of interstitial cystitis similar to those defined by National Institutes of Arthritis, Diabetes, Digestive and Kidney Diseases criteria were reviewed. Some articles describing animal models with similar pathological conditions in other organs were also included to enlarge the base of potentially relevant material. We identified and evaluated some 16 animal models of interstitial cystitis, which we categorized as bladder inflammation induced by intravesical administration of an irritant or immune stimulant, systemic and environmentally induced inflammation, and a naturally occurring model of interstitial cystitis that occurs in cats. Some abnormalities identified in humans and cats with interstitial cystitis can be reproduced in healthy animals using luminal, systemic or environmental stimuli. At the level of the bladder the source of stimulation cannot be discriminated. Variability in the extent of bladder
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://etd.ohiolink.edu/!etd.send_file?accession=osu1117044773&disposition=inline
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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