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Small bowel malignancy in patients undergoing capsule endoscopy at a tertiary care academic center: Case series and review of the literature
| Content Provider | Semantic Scholar |
|---|---|
| Author | Johnston, Connor A. Yung, Diana E. Joshi, Alka Plevris, J. N. Koulaouzidis, Anastasios |
| Copyright Year | 2017 |
| Abstract | BACKGROUND AND STUDY AIMS Small bowel cancer is rare, accounting for < 5 % of all gastrointestinal neoplasms. Capsule endoscopy has become the procedure of choice for non-invasive diagnosis of small bowel diseases. Data on capsule endoscopy diagnosis of small bowel cancer are limited. The objective of the study was to determine the frequency, indications and diagnostic work-up of patients with small bowel malignancy found by capsule endoscopy at a Scottish tertiary center. PATIENTS AND METHODS In this retrospective study, records all patients who underwent small bowel capsule endoscopy at our center over a 10-year period were reviewed for possible malignancy. Further data were gathered on preceding and subsequent investigations, management and outcome of these patients. RESULTS From 1949 studies, small bowel malignancies were diagnosed in only 7 patients (0.36 %; 2F/5M; median age 50, range 34 - 67). The main indication was iron-deficiency anemia (n = 5). Prior to capsule endoscopy, 6 of 7 patients had bidirectional endoscopies and one had gastroscopy. All prior investigations were normal or nondiagnostic. Two of 7 experienced capsule retention. Five of 7 underwent surgery. Four patients died, giving a 5-year survival rate of 42.9 %. CONCLUSION Small bowel malignancies diagnosed by capsule endoscopy are rare, and the median age of 50 indicates they are more common in relatively younger patients. Capsule endoscopy is effective at diagnosing a rare malignancy when other imaging modalities have failed. |
| Starting Page | E463 |
| Ending Page | E470 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| PubMed reference number | 28573179v1 |
| Alternate Webpage(s) | https://doi.org/10.1055/s-0043-106186 |
| DOI | 10.1055/s-0043-106186 |
| Journal | Endoscopy international open |
| Volume Number | 5 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Capsule Endoscopy Cessation of life Endoscopy (procedure) Endoscopy of stomach Gastrointestinal Neoplasms Inflammatory Bowel Diseases Intestinal Cancer Intestinal Diseases Intestines Intestines, Small Iron deficiency anemia Irritable Bowel Syndrome Non-Small Cell Lung Carcinoma Patients Small Intestinal Wall Tissue Small intestine carcinoma Tertiary Healthcare |
| Content Type | Text |
| Resource Type | Article |
