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IMPs, VIMs and SPMs: the diversity of metallo-beta-lactamases produced by carbapenem-resistant Pseudomonas aeruginosa in a Brazilian hospital.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Silbert, Suzane Gales, Ana Cristina |
| Copyright Year | 2005 |
| Abstract | Pseudomonas aeruginosa isolates (n=183), collected from bacteraemic patients hospitalised in Sao Paulo Hospital (Brazil) during 2000-2001, were screened for susceptibility to antimicrobial agents. The polymyxins were the most active compounds (100% susceptibility), followed by amikacin and cefepime (59.0%), meropenem (57.4%), and imipenem and gentamicin (55.2%). Imipenem-resistant isolates were ribotyped and screened for production of metallo-beta-lactamases (MBLs) by PCR with primers for bla(IMP), bla(VIM) and bla(SPM). MBL production was detected in 36 isolates (19.7% of the entire collection; 43.9% of the imipenem-resistant isolates) and the MBLs included SPM-1-like (55.6%), VIM-2-like (30.6%) and IMP-1-like (8.3%) enzymes. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://core.ac.uk/download/pdf/82329592.pdf |
| PubMed reference number | 15649310v1 |
| Volume Number | 11 |
| Issue Number | 1 |
| Journal | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Amikacin Carbapenems Gentamicins Imipenem Microbicides Patients Polymyxins beta Thalassemia beta-Lactamase cefepime meropenem |
| Content Type | Text |
| Resource Type | Article |
