NDLI: Unilateral lesion of the subthalamic nucleus enhances cortical fos expression associated with focally evoked seizures in the rat

Content Provider	Semantic Scholar
Author	Blandini, Fabio Fancellu, Roberto Armentero, Marie-Therese Tassorelli, Cristina Nappi, Giuseppe
Copyright Year	2006
Abstract	Reducing subthalamic nucleus (STN) activity has been proposed as an anti-epileptic procedure. Here we show that, on the contrary, a unilateral lesion of the STN causes slight (nonsignificant) increases in the severity of limbic seizures evoked by bicuculline infusion into the piriform cortex, associated with marked Fos expression throughout the cerebral cortex. Abolishing the STN control over the basal ganglia output may therefore play a facilitatory role on cortical activation associated with limbic seizures.
Starting Page	145
Ending Page	150
Page Count	6
File Format	PDF HTM / HTML
DOI	10.1016/j.brainres.2006.05.025
PubMed reference number	16782074
Journal	Medline
Volume Number	1101
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S000689930601403X
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S000689930601403X?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/j.brainres.2006.05.025
Journal	Brain Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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Unilateral lesion of the subthalamic nucleus enhances cortical fos expression associated with focally evoked seizures in the rat