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Isotope-selective non-dispersive infrared spectrometry for detection of Helicobacter pylori infection with 13C-urea breath test
| Content Provider | Semantic Scholar |
|---|---|
| Author | Koletzko, Sibylle Koletzko, Berthold Haisch, Michael Hering, Peter |
| Copyright Year | 1995 |
| Abstract | 13C-urea breath tests were sampled in 51 subjects with an isotope-selective non-dispersive infrared spectrometer (NDIRS) and compared with the results of conventional isotope-ratio mass-spectrometry (IRMS). Delta-over-baseline values of both methods correlated well (r = 0.976 at 15 min and 0.985 at 30 min, both p < 0.0005). With a cut-off for delta-over-baseline values of 5/1000 (i. e., 5 per thousand), both methods correctly classified all 36 Helicobacter-pylori-negative and all 15 H-pylori-positive subjects. All infected subjects had values over 11/1000 in all samples with both methods. NDIRS is of equal value as IRMS for the diagnosis of H pylori infection. Because NDIRS gives on-line results and is easier and cheaper, we consider NDIRS useful for clinical practice. |
| Starting Page | 961 |
| Ending Page | 962 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0140-6736(95)90704-1 |
| PubMed reference number | 7715299 |
| Journal | Medline |
| Volume Number | 345 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S0140673695907041 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S0140673695907041?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/S0140-6736%2895%2990704-1 |
| Journal | The Lancet |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
