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Epigenetic regulation of gene expression
| Content Provider | Semantic Scholar |
|---|---|
| Author | McKnight, Robert A. |
| Copyright Year | 2010 |
| Abstract | "We still do not have in our hands the answer to a most fundamental question: What makes us human? " Unconventional Mechanisms of Regulation in the CNS Comparison of the chimp and human genomes • only 1.23% of nucleotide bases differ • the average protein differs by only two amino acids • 29% of proteins are identical • the vast majority of changes between humans and chimps appear to be neutral Epigenetics In mod ern sense the term 'epigenetics' describes the study of heritable changes in genome function that occur without a change in nucleotide sequence within the DNA. Epigenome The epigenome is the overall epigenetic state of a cell. As one embryo can g enerate a multitude of cell fates during development, one genome could be said to give rise to many epigenomes. |
| File Format | PDF HTM / HTML |
| Volume Number | 24 |
| Alternate Webpage(s) | http://www.bristol.ac.uk/phys-pharm-neuro/media/teaching/korneevbristol2009.pdf |
| Alternate Webpage(s) | https://static-content.springer.com/esm/art:10.1186%2F1868-7083-4-4/MediaObjects/13148_2012_13_MOESM1_ESM.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
