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Synthesis of 2,5‐Disubstituted 1,3,4‐Oxadiazoles as Biologically Active Heterocycles.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kagthara, Preeli R. Shah, Niraj Doshi, Rajeev K. Parekh, Hansa |
| Copyright Year | 1999 |
| Abstract | 2-( 8enzimidazo l-2 '-yl) benzoyl hydrazide 1 when co ndensed with aromatic ac id s in th e presence of POCI .) afforde d 2aryl -5- 12'- benzimidazol-2"-y l) phen yll -l, 3, 4-oxadiazoles 2a-o. The ac id hydraz ide 1 on cycli sa tion wit h CNSr yiel d 2amin o- 5-[2'-(benz imidazo l-2 " -y l-phenyl)- I, 3, 4-oxadiazole 3 whi ch on reac ti on with aryl sulphon yl chlorides and substituted ben zoy l chl oride give the corres pondin g su lphonaillid es 4a-o and amides 5a-o, re spec tivel y. AI ! the produ cts have been evaluated ill I'i ll ·o fo r the ir ant imi crobi al activity aga in st several microbes and antit ubercu lar ac tivi ty aga in st |
| Starting Page | 572 |
| Ending Page | 576 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/chin.199943127 |
| Volume Number | 30 |
| Alternate Webpage(s) | http://nopr.niscair.res.in/bitstream/123456789/16448/1/IJCB%2038B(5)%20572-576.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/chin.199943127 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |