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Label-free detection of Babesia bovis infected red blood cells using impedance spectroscopy on a microfabricated flow cytometer.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Küttel, Claudia Nascimento, Elisabete M. Demierre, Nicolas Silva, Tiago Da Ponte Braschler, Thomas Renaud, Philippe Oliva, Abel Martin Gonzalez |
| Copyright Year | 2007 |
| Abstract | Impedance spectroscopy is a powerful tool for label-free analysis and characterisation of living cells. In this work, we achieved the detection of Babesia bovis infected red blood cells using impedance spectroscopy on a microfabricated flow cytometer. The cellular modifications caused by the intracellular parasite result in a shift in impedance which can be measured dielectrically. Thus, a rapid cell-by-cell detection with microliter amounts of reagents is possible. Unlike other diagnostic tests, this method does not depend on extensive sample pre-treatment or expensive chemicals and equipment. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.actatropica.2007.03.002 |
| Alternate Webpage(s) | https://infoscience.epfl.ch/record/104864/files/Kuttel_ActaTr07_Babesia.pdf |
| PubMed reference number | 17451631 |
| Alternate Webpage(s) | https://doi.org/10.1016/j.actatropica.2007.03.002 |
| Journal | Medline |
| Volume Number | 102 |
| Issue Number | 1 |
| Journal | Acta tropica |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
