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Microwave assisted novel synthesis and antibacterial evaluation of 1-( 2-methyl-2 , 5-substituted diphenyl-1 , 3 , 4-oxadiazol-3 ( 2 H )-yl ) ethanone derivatives
| Content Provider | Semantic Scholar |
|---|---|
| Author | Piste, Pravina B. Waghamale, Shubhangi P. |
| Copyright Year | 2016 |
| Abstract | In continuation of our interest regarding microwave assisted synthesis, we have carried out Novel synt hesis of 1-(2methyl-2, 5 substituted diphenyl-1, 3, 4-oxadiazol3(2H)-yl) ethanone derivatives (4a–4i) by cyclisation of N'-[(1Z)1-(substituted phenyl) ethylidene] benzohydrazide d erivatives (3a-3i) in presence of acetic anhydride on solid support silica gel under the microwave radiation. A ll the synthesized compounds were characterised on the basis IR, H NMR, C NMR and Mass spectral analysis also synthesized c ompounds were screened for their antibacterial activity against Gram positive and Gram negative ba cteria. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.jocpr.com/articles/microwave-assisted-novel-synthesis-and-antibacterial-evaluation-of-12methyl25substituted-diphenyl134oxadiazol32hylethano.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |