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Effects of lesions of locus coeruleus/subcoeruleus on diffuse noxious inhibitory controls in the rat
| Content Provider | Semantic Scholar |
|---|---|
| Author | Bouhassira, Didier Bing, Zhu Bars, Daniel Le |
| Copyright Year | 1992 |
| Abstract | Diffuse noxious inhibitory controls (DNIC) acting on trigeminal convergent neurons were compared in sham-operated animals and rats with quinolinic acid induced lesions of the locus coeruleus/subcoeruleus (LC/SC). No significant differences were observed between control animals and those with ipsilateral, contralateral or bilateral lesions of the LC/SC, in respect of: (1) the general properties of the recorded units; and (2) the magnitude of the depressions of C-fiber-evoked responses of convergent neurons produced by immersing each paw in a 50 degrees C water bath (i.e. DNIC). It is concluded that the LC/SC is not involved, at least directly, in the supraspinal part of the loop which subserves DNIC in the rat. |
| Starting Page | 140 |
| Ending Page | 144 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0006-8993(92)90520-J |
| PubMed reference number | 1611486 |
| Journal | Medline |
| Volume Number | 571 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/000689939290520J |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/000689939290520J?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0006-8993%2892%2990520-J |
| Journal | Brain Research |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
