Loading...
Please wait, while we are loading the content...
Similar Documents
Les Maladies Auto Immunes et de Système au Service de Rhumatologie du Centre Hospitalier Universitaire de Brazzaville
| Content Provider | Semantic Scholar |
|---|---|
| Author | N’soundhat, Norbert Edgard Lamini Ntsiba, Honoré |
| Copyright Year | 2020 |
| Abstract | RESUME Objectif. Decrire le profil des affections auto-immunes et de systemes vus en Rhumatologie a Brazzaville. Patients et methodes. Etude transversale descriptive sur dossiers medicaux, menee dans le service de Rhumatologie du Centre Hospitalier Universitaire de Brazzaville au Congo, portant sur des patients suivis en consultation specialisee des maladies auto-immunes et de systemes, de janvier 2011 a juin 2017 (6 ans et 6 mois). Le diagnostic etait base les arguments cliniques et para cliniques definis par l’ACR. Resultats. Nous avons etudie 90 patients dont 80 patients de sexe feminin (89%) et 10 de sexe masculin (11%). L’âge moyen etait de 40,09 +/- 15,07 ans (extremes 5 et 78 ans). Le motif de consultation etait des polyarthralgies inflammatoires dans 62 cas (68,8%) et une polyarthrite dans 23 cas (25,5%). Les principaux diagnostics retenus etaient une connectivite dans 38 cas (42,2%), une polyarthrite rhumatoide dans 33 cas (36,6 %), une vascularite systemique dans 9 cas (9,9%). Elle se compliquait de sepsis dans 16 cas (17,7%), de nephropathie dans 13 cas (14,4%) et de pneumopathie infiltrative diffuse dans 6 cas (6,6%). Le traitement comportait une corticotherapie generale chez 88 patients (97,7%), le methotrexate chez 45 patients (50%), l’hydroxychloroquine dans 41 cas (45,5%). Six patients ont ete mis sous azathioprine (6,6%) et cinq sous cyclophosphamide (5,5%). Le traitement a provoque des effets indesirables chez 4 patients (4,4%): rash cutane (2 cas), cytolyse hepatique (2 cas). Durant la periode d’etude, trois patients sont decedes. Conclusion. Les connectivites sont le principal groupe pathologique. Les infections emaillaient frequemment leur evolution de ces affections. ABSTRACT Objective. To describe the pattern of autoimmune and systems diseases seen in Rheumatology in Brazzaville. Patients and methods. This was a cross sectional study on medical records, conducted in the Rheumatology Department of the University Teaching Hospital of Brazzaville in Congo, involving patients followed by specialized consultations on autoimmune and systems diseases, from January 2011 to June 2017 (6 years and 6 months) . The diagnosis was based on clinical and para-clinical arguments defined by the ACR. Results. We studied 90 patients among whom 80 females (89%) and 10 males (11%). The average age was 40.09 +/- 15.07 years (range 5 to 78 years). The reason for consultation was inflammatory polyarthralgia in 62 cases (68.8%) and polyarthritis in 23 cases (25.5%). The main diagnoses were connective tissue disease in 38 cases (42.2%), rheumatoid arthritis in 33 cases (36.6%), and systemic vasculitis in 9 cases (9.9%). The course was complicated by sepsis in 16 cases (17.7%), nephropathy in 13 cases (14.4%) and diffuse infiltrative pneumopathy in 6 cases (6.6%). The treatment included systemic corticosteroids in 88 patients (97.7%), methotrexate in 45 patients (50%) and hydroxychloroquine in 41 cases (45.5%). six patients were given azathioprine (6.6%) and 5 cyclophosphamide (5.5%). The treatment was responsible for undesirable effects in 4 patients (4.4%): skin rash (2 cases), hepatic cytolysis (2 cases). During the study period, three patients died. Conclusion. Connectivites are the main diseases. The course in frequently complicated by infections. |
| File Format | PDF HTM / HTML |
| Volume Number | 21 |
| Alternate Webpage(s) | https://www.hsd-fmsb.org/index.php/hsd/article/download/1956/1514 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
