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Elementary properties of axonal calcium currents in type B photoreceptors in Hermissenda crassicornis.
| Content Provider | Semantic Scholar |
|---|---|
| Copyright Year | 2002 |
| Abstract | Axons of the type B photoreceptors form synapses with hair cells and interneurons that are involved in classical conditioning in Hermissenda. We examined the differences in the Ca2+ channels expressed in the soma and axons of the B photoreceptors by direct functional recordings of single-channel currents. Although the soma of the B cells express two Ca2+ current subtypes, a transient BayK 8644-insensitive (approximately 17 pS) current and a sustained BayK 8644-sensitive (approximately 10 pS) current, the axons expressed only the latter. The axonal Ca2+ current activated at potentials positive to -20 mV. Moreover, the Ca2+ channels are distributed heterogeneously along the length of the axon, with the higher channel density (approximately 10-15 channel microm(-2)) occurring at the distal one-third of the isolated axons, with respect to the soma. The regions of Ca2+ channel clusters may represent the presynaptic site of the photoreceptor-interneuron synapses. Furthermore, the high-density clusters of Ca2+ channels may augment postsynaptic responses. The results of the present study represent the first direct recordings of Ca2+ currents at presumed synaptic sites. Expression of different Ca2+ channel subtypes at distinct compartments of the type B photoreceptors may generate diverse Ca2+ domains that may be required for neuronal plasticity in Hermissenda. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.jneurosci.org/content/jneuro/22/24/10533.full.pdf |
| PubMed reference number | 12486145v1 |
| Volume Number | 22 |
| Issue Number | 24 |
| Journal | The Journal of neuroscience : the official journal of the Society for Neuroscience |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Anatomical compartments Auditory Hair Cell Axon Calcium ion Cell body of neuron Conditioning (Psychology) Conditioning, Classical Hermissenda Interneurons Neuronal Plasticity Nomamyrmex esenbeckii Photoreceptors Subtype (attribute) Synapses |
| Content Type | Text |
| Resource Type | Article |
