NDLI: A monoclonal antibody to common acute lymphoblastic leukemia antigen (CALLA) and its expression on several human tumor cell lines.

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A monoclonal antibody to common acute lymphoblastic leukemia antigen (CALLA) and its expression on several human tumor cell lines.

Content Provider	Semantic Scholar
Author	Park, Weon Seo Hwang, Tea Sook Park, Chang-Soo Bae, Young Mee Park, Seong Hoe Lee, Sang Koo
Copyright Year	1992
Abstract	We describe a newly-made murine monoclonal antibody to the common acute lymphoblastic leukemia antigen (CALLA), named SHB-10. The antigen detected by SHB-10 has a molecular weight of about 105 kDa. This antibody is very similar to that of conventional anti-CD10 Ab on indirect flowcytometric analysis using lymphoid malignant cell lines and peripheral lymphocytes of acute lymphoblastic leukemia (ALL) patients. The binding of anti-CD10 to Daudi cell and peripheral lymphocytes of ALL patients is blocked by SHB-10. Thus this monoclonal antibody is thought to detect the CALLA. The distribution of antigen detected by SHB-10 on several cell lines of neuroectodermal tumor and lymphoid malignancy was analysed and a slight difference in their cell surface expression is observed when compared with that by conventional anti-CD10. Further biochemical analysis is now under way for a better characterization of this antigen.
Starting Page	147
Ending Page	153
Page Count	7
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://ftp.ncbi.nlm.nih.gov/pub/pmc/bf/76/1388026.PMC3053825.pdf
Alternate Webpage(s)	https://synapse.koreamed.org/Synapse/Data/PDFData/0063JKMS/jkms-7-147.pdf
PubMed reference number	1388026
Volume Number	7
Journal	Journal of Korean medical science
Language	English
Access Restriction	Open
Subject Keyword	Acute lymphocytic leukemia Cell Line, Tumor Cultured Cell Line Human Neprilysin Leukemia, B-Cell Leukemia, Myelocytic, Acute Molecular Weight Monoclonal Antibodies Name Neoplasms Neuroectodermal Tumor, Primitive Patients Precursor Cell Lymphoblastic Leukemia Lymphoma Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Pseudolymphoma cancer cell lymphoblast trastuzumab
Content Type	Text
Resource Type	Article

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