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A fluorescent probe for ratiometric imaging of exogenous and intracellular formed hypochlorous acid in lysosomes
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ren, Mingguang Nie, Jing Deng, Beibei Zhou, Kai Zhi Wang, Jian-Yong Lin, Weiying |
| Copyright Year | 2017 |
| Abstract | We have developed a new lysosome-targeting ratiometric fluorescent probe (FL-HA) for specific determination of HOCl in living cells. The developed probe exhibits accurate lysosome-targeting ability, good signal resolution, and high selectivity. Moreover, fluorescence imaging shows that FL-HA could be used as a probe for ratiometric visualization of exogenous and endogenous HOCl in lysosomes with a high colocalization coefficient compared with a commercial lysosomal location dye. |
| Starting Page | 5259 |
| Ending Page | 5262 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/C7NJ00949F |
| Volume Number | 41 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c7/nj/c7nj00949f/c7nj00949f1.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/C7NJ00949F |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |