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Fabrication of nanoscale zero-mode waveguides using microlithography for single molecule sensing.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Teng, Chu-Hsiang Lionberger, Troy A. Zhang, Jin Meyhöfer, Edgar Ku, Pei-Cheng |
| Copyright Year | 2012 |
| Abstract | We present a novel approach to the fabrication of zero-mode waveguides (ZMWs) using inexpensive processing techniques. Our method is capable of rapid fabrication of circular nanoapertures with diameters ranging from 70 nm to 2 μm, allowing us to perform a detailed characterization of the dependence of the fluorescence emission on the waveguide diameter. We also validated the use of the fabricated ZMWs by detecting single molecule binding events with a signal-to-noise ratio of ten. |
| Starting Page | 455301 |
| Ending Page | 455301 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| DOI | 10.1088/0957-4484/23/45/455301 |
| PubMed reference number | 23085680 |
| Journal | Medline |
| Volume Number | 23 |
| Issue Number | 45 |
| Alternate Webpage(s) | https://deepblue.lib.umich.edu/bitstream/handle/2027.42/98608/0957-4484_23_45_455301.pdf?sequence=1 |
| Alternate Webpage(s) | https://doi.org/10.1088/0957-4484%2F23%2F45%2F455301 |
| Journal | Nanotechnology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |