NDLI: EFEITO DA QUERCETINA SOBRE O CRESCIMENTO E ATIVIDADE HEMOLÍTICA DE Staphylococcus aureus

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EFEITO DA QUERCETINA SOBRE O CRESCIMENTO E ATIVIDADE HEMOLÍTICA DE Staphylococcus aureus

Content Provider	Semantic Scholar
Author	Camargo, Mariana Santoro De Raddi, Maria Stella Gonçalves
Copyright Year	2010
Abstract	RESUMO: Os flavonoides sao compostos polifenolicos com ampla distribuicao no reino vegetal. Quercetina, composto pertencente a classe dos flavonois, esta presente em diversos alimentos e exerce multiplas atividades farmacologicas. Em decorrencia da necessidade de novas opcoes terapeuticas nas doencas infecciosas, enfase no estudo da atividade antimicrobiana de flavonoides teve destaque nos ultimos anos. Esse estudo avaliou o efeito pos-antimicrobiano (EPA) e modulacao na atividade de hemolisinas da concentracao subinibitoria de quercetina em Staphylococcus aureus (ATCC 25923). A atividade antibacteriana foi determinada atraves do metodo de microdiluicao em caldo, sendo a concentracao de 40µ/mL utilizada como subinibitoria. Quercetina demonstrou nao apresentar EPA nessa concentracao, mas diminuiu a atividade de hemolisinas extracelulares para hemacias de carneiro. Essas observacoes sugerem que outras toxinas danificadoras de membrana relacionadas a virulencia de S. aureus possam ser moduladas por esse flavonol, interferindo na capacidade do microrganismo em danificar o hospedeiro. 10.5216/ref.v5i3.12366
File Format	PDF HTM / HTML
DOI	10.5216/ref.v5i3.12366
Alternate Webpage(s)	https://revistas.ufg.br/REF/article/download/12366/8139
Alternate Webpage(s)	https://doi.org/10.5216/ref.v5i3.12366
Volume Number	5
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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