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Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Perilli, Mariagrazia Caporale, Bibiana Celenza, Giuseppe Pellegrini, Cristina Docquier, Jean Denis Mezzatesta, Marilina Rossolini, Gian Maria Stefani, Stefania Amicosante, Gianfranco |
| Copyright Year | 2007 |
| Abstract | A new natural IND-type metallo-beta-lactamase variant, IND-5, was identified in a clinical isolate of Chryseobacterium indologenes. IND-5 shared 92.8% and 92.4% amino acid homology with IND-1 and IND-3, respectively. Purified enzyme (pI = 8.8, M(r) = 25,000) was able to hydrolyze penicillins, some narrow- and expanded-spectrum cephalosporins, and carbapenems but not monobactams. |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/AAC.00083-07 |
| PubMed reference number | 17470648 |
| Journal | Medline |
| Volume Number | 51 |
| Issue Number | 8 |
| Alternate Webpage(s) | http://aac.asm.org/content/51/8/2988.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1128/AAC.00083-07 |
| Journal | Antimicrobial agents and chemotherapy |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |