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Predictors of recurrent restenosis after second-generation drug-eluting stent implantation for in-stent restenosis of drug-eluting stents
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kadota, Kazushige Habara, Seiji Tada, Takeshi Tanaka, Hiroyuki Fuku, Yasushi Goto, Tsuyoshi Mitsudo, Kazuaki |
| Copyright Year | 2016 |
| Abstract | Aims: The aim of the study was to evaluate predictors of recurrent restenosis after second-generation drugeluting stent (DES) implantation for in-stent restenosis (ISR) of DES. Methods and results: We retrospectively investigated 228 consecutive patients undergoing second-generation DES implantation for ISR of DES. There were 285 lesions in total and the implanted stents were as follows: biolimus-eluting stent, 71; everolimus-eluting stent, 214. We performed eight-month follow-up on 241 lesions (84.6%). The primary angiographic endpoint was binary restenosis, which was defined as ≥50% stenosis at follow-up angiography. Of the 241 lesions, recurrent restenosis was documented in 54 lesions (22.4%), and target lesion revascularisation was performed in 39 lesions (16.2%). Multivariate analysis showed that small vessel (odds ratio [OR] 2.21; 95% confidence interval [CI]: 1.12 to 4.40; p=0.02) and non-focal type restenosis (OR 2.78; 95% CI: 1.36 to 5.78; p=0.0048) were independent predictors of recurrent restenosis. The type of second-generation DES, whether a biolimus-eluting stent or an everolimus-eluting stent, did not affect the angiographic outcomes (OR 0.80; 95% CI: 0.37-1.78; p=0.58). Conclusions: Small vessel and non-focal type restenosis are predictors of recurrent restenosis after second-generation DES implantation for ISR of DES. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.asiaintervention.org/wp-content/uploads/2016/09/webAIJ24_20160112_01_KanazawaCR.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
