NDLI: Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies

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Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies—Statement From ATVB Council

Content Provider	Scilit
Author	Robinet, Peggy Milewicz, Dianna M. Cassis, Lisa A. Leeper, Nicholas J. Lu, Hong S. Smith, Jonathan D.
Copyright Year	2018
Description	Journal: Arteriosclerosis, thrombosis, and vascular biology There are many differences in arterial diseases between men and women, including prevalence, clinical manifestations, treatments, and prognosis. The new policy of the National Institutes of Health, which requires the inclusion of sex as a biological variable for preclinical studies, aims to foster new mechanistic insights and to enhance our understanding of sex differences in human diseases. The purpose of this statement is to suggest guidelines for designing and reporting sex as a biological variable in animal models of atherosclerosis, thoracic and abdominal aortic aneurysms, and peripheral arterial disease. We briefly review sex differences of these human diseases and their animal models, followed by suggestions on experimental design and reporting of animal studies for these vascular pathologies.
Related Links	https://www.ahajournals.org/doi/pdf/10.1161/ATVBAHA.117.309524 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785439/pdf https://www.ahajournals.org/doi/reader/10.1161/ATVBAHA.117.309524
Ending Page	303
Page Count	12
Starting Page	292
ISSN	10795642
e-ISSN	15244636
DOI	10.1161/atvbaha.117.309524
Journal	Arteriosclerosis, thrombosis, and vascular biology
Issue Number	2
Volume Number	38
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publisher Date	2018-02-01
Access Restriction	Open
Subject Keyword	Journal: Arteriosclerosis, thrombosis, and vascular biology Peripheral Vascular Disease Peripheral Arterial Disease
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine

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