Loading...
Please wait, while we are loading the content...
Similar Documents
Correlation between adenoma detection rate in colonoscopy‐ and fecal immunochemical testing‐based colorectal cancer screening programs
| Content Provider | Scilit |
|---|---|
| Author | Cubiella, Joaquín Castells, Antoni Andreu, Montserrat Bujanda, Luis Carballo, Fernando Jover, Rodrigo Lanas, Ángel Morillas, Juan Diego Salas, Dolores Quintero, Enrique |
| Copyright Year | 2017 |
| Description | Journal: United European Gastroenterology Journal The adenoma detection rate (ADR) is the main quality indicator of colonoscopy. The ADR recommended in fecal immunochemical testing (FIT)-based colorectal cancer screening programs is unknown. Using the COLONPREV (NCT00906997) study dataset, we performed a post-hoc analysis to determine if there was a correlation between the ADR in primary and work-up colonoscopy, and the equivalent figure to the minimal 20% ADR recommended. Colonoscopy was performed in 5722 individuals: 5059 as primary strategy and 663 after a positive FIT result (OC-Sensor™; cut-off level 15 µg/g of feces). We developed a predictive model based on a multivariable lineal regression analysis including confounding variables. The median ADR was 31% (range, 14%-51%) in the colonoscopy group and 55% (range, 21%-83%) in the FIT group. There was a positive correlation in the ADR between primary and work-up colonoscopy (Pearson's coefficient 0.716; p < 0.001). ADR in the FIT group was independently related to ADR in the colonoscopy group: regression coefficient for colonoscopy ADR, 0.71 (p = 0.009); sex, 0.09 (p = 0.09); age, 0.3 (p = 0.5); and region 0.00 (p = 0.9). The equivalent figure to the 20% ADR was 45% (95% confidence interval, 35%-56%). ADR in primary and work-up colonoscopy of a FIT-positive result are positively and significantly correlated. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349366/pdf |
| Ending Page | 260 |
| Page Count | 6 |
| Starting Page | 255 |
| e-ISSN | 20506414 |
| DOI | 10.1177/2050640616660662 |
| Journal | United European Gastroenterology Journal |
| Issue Number | 2 |
| Volume Number | 5 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2017-03-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: United European Gastroenterology Journal Gastroenterology and Hepatology Colorectal Adenoma Adenoma Detection Rate Colorectal Cancer Screening Colorectal Neoplasm Fecal Immunochemical Test |
| Content Type | Text |
| Resource Type | Article |
