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Prevalence of overlap syndrome in chronic obstructive pulmonary disease patients without sleep apnea symptoms
| Content Provider | Scilit |
|---|---|
| Author | Gunduz, Canan Basoglu, Ozen K. Tasbakan, Mehmet Sezai |
| Copyright Year | 2016 |
| Description | Journal: The Clinical Respiratory Journal Background: The co-existence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is a common phenomenon referred to as overlap syndrome (OS). In the present study, we evaluated the prevalence of OS in mild hypoxemic COPD patients without OSA symptoms and compared characteristics of OS and COPD patients.Methods: Forty five COPD patients (mean FEV1 1671.3±532.0 ml) with mild hypoxemia presenting no sleep apnea symptoms (96% men, mean age 67.7±8.5 years) were involved in this study. Clinical characteristics were recorded, biochemical analysis and polygraphy were performed.Results: Twenty-six patients with a RDI of ≥15 events/h were defined as OS (58%). When OS (n=26) and COPD without OSA (n=19) groups were compared, BMI (29.6±6.6 vs. 25.6±4.9kg/m2; p=0.03), TNF-α level (24.8±8.1 vs. 3.6±0.8 ng/ml; p=0.03) and sleep time with SpO227.2 kg/m2 had a sensitivity of 73% and specificity of 68%.Conclusions: The present findings support that high prevalence (58%) of OS in COPD patients without OSA symptoms is related to BMI. Therefore, sleep study should be considered in especially overweight or obese COPD patients, even in those without sleep apnea symptoms. This article is protected by copyright. All rights reserved. |
| Related Links | http://onlinelibrary.wiley.com/doi/10.1111/crj.12493/pdf |
| Ending Page | 112 |
| Page Count | 8 |
| Starting Page | 105 |
| e-ISSN | 1752699X |
| DOI | 10.1111/crj.12493 |
| Journal | The Clinical Respiratory Journal |
| Issue Number | 1 |
| Volume Number | 12 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2016-06-06 |
| Access Restriction | Open |
| Subject Keyword | Journal: The Clinical Respiratory Journal Chronic Obstructive Lung Disease Overlap Syndrome Obstructive Sleep Apnea Mild Hypoxemia |
| Content Type | Text |
| Resource Type | Article |
