NDLI: WT1 expression at diagnosis does not predict survival in pediatric aml: A report from the Children's Oncology Group

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WT1 expression at diagnosis does not predict survival in pediatric aml: A report from the Children's Oncology Group

Content Provider	Scilit
Author	Noronha, Suzie A. Farrar, Jason E. Alonzo, Todd A. Gerbing, Robert B. Lacayo, Norman J. Dahl, Gary V. Ravindranath, Yaddanapudi Arceci, Robert J. Loeb, David M.
Copyright Year	2009
Description	Journal: Pediatric Blood & Cancer WT1 is a transcription factor that is aberrantly overexpressed in acute and chronic leukemias. Overexpression of WT1 in pediatric acute myeloid leukemia has been reported, but the prognostic significance is unclear because sample sizes in these studies have been relatively small. WT1 expression was measured by quantitative RT-PCR in samples obtained at diagnosis from 155 pediatric AML patients treated on a cooperative group protocol. Neither overall survival nor event-free survival was correlated with WT1 expression.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926132/pdf
Ending Page	1139
Page Count	4
Starting Page	1136
e-ISSN	15455017
DOI	10.1002/pbc.22142
Journal	Pediatric Blood & Cancer
Issue Number	6
Volume Number	53
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2009-07-17
Access Restriction	Open
Subject Keyword	Journal: Pediatric Blood & Cancer Pediatrics and Child Health Wilms Tumor 1 Acute Myeloid Leukemia Prognostic Factor
Content Type	Text
Resource Type	Article

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