NDLI: Review article: the relevance of surveillance endoscopy in long-lasting inflammatory bowel disease

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Review article: the relevance of surveillance endoscopy in long-lasting inflammatory bowel disease

Content Provider	Scilit
Author	Vleggaar, F. P. Lutgens, M. W. M. D. Claessen, M. M. H.
Copyright Year	2007
Description	Journal: Alimentary Pharmacology & Therapeutics Development of colitis-associated colorectal cancer is an important clinical problem in patients with colonic inflammatory bowel disease (IBD). British and American guidelines recommend to start surveillance after a disease duration of 8-10 or 15-20 years for patients with extensive or left-sided colitis, respectively. To assess the evidence level of current surveillance strategies. A PubMed-based literature search using the search terms inflammatory bowel disease, ulcerative colitis, Crohn's disease, dysplasia, colorectal cancer and surveillance was performed. Low-grade and high-grade dysplastic lesions progress to cancer in a high percentage of patients. Furthermore, concurrent cancer is found in approximately one-third of the patients with colonic dysplasia. Low-level evidence showing reduced colorectal cancer-related mortality in patients who were undergoing surveillance is available. Patients with concomitant primary sclerosing cholangitis form a subgroup of IBD patients with an even higher risk of colorectal neoplasia. Colonic surveillance prolongs life expectancy of patients with long-lasting IBD.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2007.03487.x/pdf
Ending Page	52
Page Count	6
Starting Page	47
e-ISSN	13652036
DOI	10.1111/j.1365-2036.2007.03487.x
Journal	Alimentary Pharmacology & Therapeutics
Volume Number	26
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2007-12-07
Access Restriction	Open
Subject Keyword	Journal: Alimentary Pharmacology & Therapeutics Gastroenterology and Hepatology Inflammatory Bowel Disease Colorectal Cancer Ulcerative Colitis Guidelines Recommend Expectancy of Patients
Content Type	Text
Resource Type	Article

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