NDLI: Occupational exposures and chronic kidney disease: Possible associations with endotoxin and ultrafine particles

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Occupational exposures and chronic kidney disease: Possible associations with endotoxin and ultrafine particles

Content Provider	Scilit
Author	Sponholtz, Todd R. Sandler, Dale P. Parks, Christine G. Applebaum, Katie M.
Copyright Year	2015
Description	Journal: American journal of industrial medicine Chronic kidney disease (CKD) carries a high public health burden yet there is limited research on occupational factors, which are examined in this retrospective case-control study. Newly diagnosed cases of CKD (n = 547) and controls (n = 508) from North Carolina provided detailed work histories in telephone interviews. Unconditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). There was heterogeneity in the association of CKD and agricultural work, with crop production associated with increased risk and work with livestock associated with decreased risk. Work with cutting/cooling/lubricating oils was associated with a reduced risk. CKD risk was increased for working in dusty conditions. CKD risk was reduced in subjects with occupational exposures previously reported to involve endotoxin exposure. Further, exposure to dusty conditions was consistently associated with increased risk of glomerulonephritis across industry, suggesting that research on CKD and ultrafine particulates is needed.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715760/pdf
e-ISSN	10970274
DOI	10.1002/ajim.22541
Journal	American journal of industrial medicine
Issue Number	1
Volume Number	59
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2015-11-17
Access Restriction	Open
Subject Keyword	Journal: American journal of industrial medicine Occupational Exposures
Content Type	Text
Resource Type	Article

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