NDLI: Collaboration and competition between DNA double-strand break repair pathways

Please wait, while we are loading the content...

Collaboration and competition between DNA double-strand break repair pathways

Content Provider	Scilit
Author	Kass, Elizabeth M. Jasin, Maria
Copyright Year	2010
Description	Journal: FEBS Letters DNA double-strand breaks resulting from normal cellular processes including replication and exogenous sources such as ionizing radiation pose a serious risk to genome stability, and cells have evolved different mechanisms for their efficient repair. The two major pathways involved in the repair of double-strand breaks in eukaryotic cells are non-homologous end joining and homologous recombination. Numerous factors affect the decision to repair a double-strand break via these pathways, and accumulating evidence suggests these major repair pathways both cooperate and compete with each other at double-strand break sites to facilitate efficient repair and promote genomic integrity.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954739/pdf
Ending Page	3708
Page Count	6
Starting Page	3703
e-ISSN	18733468
DOI	10.1016/j.febslet.2010.07.057
Journal	FEBS Letters
Issue Number	17
Volume Number	584
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2010-08-04
Access Restriction	Open
Subject Keyword	Journal: FEBS Letters Biochemistry and Molecular Biology Double-strand Break Dna Repair Non-homologous End Joining Homologous Recombination Single-strand Annealing
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in