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Salicylic acid‐enhanced biosynthesis of pharmacologically important lignans and neo lignans in cell suspension culture of Linum ussitatsimum L
| Content Provider | Scilit |
|---|---|
| Author | Nadeem, Muhammad Ahmed, Waqar Zahir, Adnan Hano, Christophe Abbasi, Bilal Haider |
| Copyright Year | 2018 |
| Description | Journal: Engineering in Life Sciences Linum usitatsimum L. (flax) is a perennial herb with magnitude of medicinal and commercial applications. In the present study, we investigated the effects of Salicylic acid (SA) on biosynthesis of lignans (secoisolariciresinol diglucoside, SDG and lariciresinol diglucoside, LDG) and neolignans (dehydrodiconiferyl alcohol glucoside, DCG and guaiacylglycerol‐β‐coniferyl alcohol ether glucoside, GGCG) in cell cultures of flax. Moderate concentration of SA (50 μM) enhanced biomass accumulation (10.98 g/L DW), total phenolic content (37.81 mg/g DW) and antioxidant potential (87.23%) to two fold than their respective controls after 72 h of exposure. However, higher levels of total flavonoid content (5.32 mg/g DW) were noted after 48h of exposure to 50μM of SA. HPLC analyses revealed that 50 μM SA, significantly enhanced biosynthesis of SDG (7.95 mg/g DW), LDG (7.52 mg/g DW), DCG (54.90 mg/g DW) and GGCG (16.78 mg/g DW), which was almost 2.7, 1.8, 3.88 and 3.98 fold higher than their respective controls after 72 h of exposure time, respectively. These results indicated that moderate concentrations of SA had significant effects on biosynthesis and productivity of lignans and neolignans in cell culture of L. usitatissimum. This article is protected by copyright. All rights reserved |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999296/pdf |
| Ending Page | 174 |
| Page Count | 7 |
| Starting Page | 168 |
| ISSN | 16180240 |
| e-ISSN | 16182863 |
| DOI | 10.1002/elsc.201800095 |
| Journal | Engineering in Life Sciences |
| Issue Number | 3 |
| Volume Number | 19 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2018-12-07 |
| Access Restriction | Open |
| Subject Keyword | Journal: Engineering in Life Sciences Biotechnology and Microbiology Linum Usitatissimum |
| Content Type | Text |
| Resource Type | Article |
| Subject | Environmental Engineering Bioengineering Biotechnology |
