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Occult B infection in the Brazilian northeastern region: a preliminary report
| Content Provider | Scilit |
|---|---|
| Author | Almeida, Delvone Tavares-Neto, José Trepo, Christian Almeida, Alessandro Mello, Caroline Chemin, Isabelle Paraná, Raymundo |
| Copyright Year | 2008 |
| Description | A sentinel study on viral hepatitis is currently being carried out in the village of Cavunge in a semiarid rural region of the state of Bahia, northeastern Brazil. This study has identified individuals in whom anti-HBc IgG was the only serological marker for hepatitis B virus (HBV). This serological pattern may constitute evidence of occult HBV infection. This study Investigated the possibility of occult hepatitis B virus infection in individuals in a rural community who tested positive for anti-HBc IgG alone. A cross-sectional population-based study. ELISA III was performed on serum samples to test for serological viral markers, and ultrasensitive PCR (US-PCR) was used to assess viremia. Among the 1,536 serum samples, 3.6% (n=55) were positive for anti-HBc alone. Four years after this first serological survey, 31 of those 55 individuals (56.3%) were retested, and 11 (35.5%) remained anti-HBc positive alone. Two of these 31 (6.5%) were HBV-DNA positive based on US-PCR, with normal aminotransferase levels in both cases. Cases of occult hepatitis B infection were identified in this semiarid rural community of northeastern Brazil, where endemicity of HBV is moderate |
| Related Links | http://www.scielo.br/pdf/bjid/v12n4/a10v12n4.pdf |
| Ending Page | 312 |
| Page Count | 3 |
| Starting Page | 310 |
| ISSN | 14138670 |
| e-ISSN | 16784391 |
| DOI | 10.1590/s1413-86702008000400010 |
| Journal | The Brazilian Journal of Infectious Diseases |
| Issue Number | 4 |
| Volume Number | 12 |
| Language | English |
| Publisher | FapUNIFESP (SciELO) |
| Publisher Date | 2008-08-01 |
| Access Restriction | Open |
| Subject Keyword | The Brazilian Journal of Infectious Diseases Hepatitis B Virus |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Microbiology (medical) |
