NDLI: Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal

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Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal

Content Provider	Scilit
Author	Romeiro, Luiz Antonio Soares Fraga, Carlos Alberto Manssour Barreiro, Eliezer J.
Copyright Year	2003
Description	Depression is a widespread humor disturbance promoted mainly by depletion of biogenic neurotransmitter amines involved in the CNS synapses. Effective drug treatments for depression have been available for more than forty years. Despite its remarkable structural diversity, this paper discuss under the medicinal chemistry point of view, all different classes of "monoamine based" antidepressant drugs, emphasizing the rational design, structure-activity relationships (SAR), biotransformation and physico-chemical properties related with antidepressant activity and molecular mechanism of action
Related Links	http://www.scielo.br/scielo.php?script=sci_pdf&pid=S0100-40422003000300012&lng=pt&nrm=iso&tlng=pt
Ending Page	358
Page Count	12
Starting Page	347
ISSN	01004042
e-ISSN	01004042
DOI	10.1590/s0100-40422003000300012
Journal	Química Nova
Issue Number	3
Volume Number	26
Language	English
Publisher	FapUNIFESP (SciELO)
Publisher Date	2003-05-01
Access Restriction	Open
Subject Keyword	Química Nova Serotonin Receptor
Content Type	Text
Resource Type	Article
Subject	Chemistry

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