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Comparison of 4 commercially available group B Streptococcus molecular assays using remnant rectal–vaginal enrichment broths

Content Provider	Scilit
Author	Relich, Ryan F. Buckner, Rebecca J. Emery, Christopher L. Davis, Thomas E.
Copyright Year	2018
Description	Journal: Diagnostic microbiology and infectious disease The incidence of neonatal Group B streptococcal (GBS) disease has significantly declined since the widespread implementation of prenatal screening of expectant mothers for urogenital and gastrointestinal tract GBS colonization. Screening methods have evolved from exclusively culture-based approaches to more rapid and highly sensitive molecular methods. We chose to evaluate the performance of 4 commercially available GBS molecular tests for detection of GBS colonization using 299 antepartum rectal–vaginal specimens submitted to our laboratory for routine GBS screening. In 97% of instances, there was agreement between all 3 systems. When testing 1, 6, and 12 samples simultaneously, all methods performed comparably, but the ARIES® GBS assay required the least total hands-on time and the $illumigene^{®}$ Group B Streptococcus assay required the most hands-on time.
Related Links	https://scholarworks.iupui.edu/bitstream/1805/15886/1/Relich_2018_comparison.pdf
Ending Page	308
Page Count	4
Starting Page	305
ISSN	07328893
e-ISSN	18790070
DOI	10.1016/j.diagmicrobio.2018.03.012
Journal	Diagnostic microbiology and infectious disease
Issue Number	4
Volume Number	91
Language	English
Publisher	Elsevier BV
Publisher Date	2018-08-01
Access Restriction	Open
Subject Keyword	Journal: Diagnostic microbiology and infectious disease Medical Laboratory Technology Group B Streptococcus Streptococcus Agalactiae Neonatal Sepsis Neonatal Meningitis Real-time Pcr
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Microbiology (medical)

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