Loading...
Please wait, while we are loading the content...
Similar Documents
Gap junction gene and protein families: Connexins, innexins, and pannexins
| Content Provider | Scilit |
|---|---|
| Author | Beyer, Eric C. Berthoud, Viviana M. |
| Copyright Year | 2018 |
| Description | Journal: Biochimica Et Biophysica Acta (bba) - Biomembranes Gap junction channels facilitate the intercellular exchange of ions and small molecules. While this process is critical to all multicellular organisms, the proteins that form gap junction channels are not conserved. Vertebrate gap junctions are formed by connexins, while invertebrate gap junctions are formed by innexins. Interestingly, vertebrates and lower chordates contain innexin homologs, the pannexins, which also form channels, but rarely (if ever) make intercellular channels. While the connexin and the innexin/pannexin polypeptides do not share significant sequence similarity, all three of these protein families share a similar membrane topology and some similarities in quaternary structure. This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704981/pdf |
| Ending Page | 8 |
| Page Count | 4 |
| Starting Page | 5 |
| ISSN | 00052736 |
| DOI | 10.1016/j.bbamem.2017.05.016 |
| Journal | Biochimica Et Biophysica Acta (bba) - Biomembranes |
| Issue Number | 1 |
| Volume Number | 1860 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2018-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Biochimica Et Biophysica Acta (bba) - Biomembranes Developmental Biology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Biochemistry Biophysics |
