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COVID-19 surveillance in Southeastern Virginia using wastewater-based epidemiology
| Content Provider | Scilit |
|---|---|
| Author | Gonzalez, Raul Curtis, Kyle Bivins, Aaron Bibby, Kyle Weir, Mark H. Yetka, Kathleen Thompson, Hannah Keeling, David Mitchell, Jamie Gonzalez, Dana |
| Copyright Year | 2020 |
| Description | Journal: Water Research Wastewater-based epidemiology (WBE) has been used to analyze markers in wastewater treatment plant (WWTP) influent to characterize emerging chemicals, drug use patterns, or disease spread within communities. This approach can be particularly helpful in understanding outbreaks of disease like the novel Coronavirus disease-19 (COVID-19) when combined with clinical datasets. In this study, three RT-ddPCR assays (N1, N2, N3) were used to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in weekly samples from nine WWTPs in southeastern Virginia. In the first several weeks of sampling, SARS-CoV-2 detections were sporadic. Frequency of detections and overall concentrations of RNA within samples increased from mid March into late July. During the twenty-one week study, SARS-CoV-2 concentrations ranged from $10^{1}$ to $10^{4}$ copies 100 $mL^{−1}$ in samples where viral RNA was detected. Fluctuations in population normalized loading rates in several of the WWTP service areas agreed with known outbreaks during the study. Here we propose several ways that data can be presented spatially and temporally to be of greatest use to public health officials. As the COVID-19 pandemic wanes, it is likely that communities will see increased incidence of small, localized outbreaks. In these instances, WBE could be used as a pre-screening tool to better target clinical testing needs in communities with limited resources. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424388/pdf |
| Ending Page | 116296 |
| Page Count | 1 |
| Starting Page | 116296 |
| ISSN | 00431354 |
| DOI | 10.1016/j.watres.2020.116296 |
| Journal | Water Research |
| Volume Number | 186 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2020-08-13 |
| Access Restriction | Open |
| Subject Keyword | Journal: Water Research Water Science and Technology Wastewater-based Epidemiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ecological Modeling Waste Management and Disposal Pollution Environmental Engineering Water Science and Technology Civil and Structural Engineering |
