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Persistence of racial disparities in early-stage lung cancer treatment
| Content Provider | Scilit |
|---|---|
| Author | Wolf, Andrea Alpert, Naomi Tran, Benjamin V. Liu, Bian Flores, Raja Taioli, Emanuela |
| Copyright Year | 2018 |
| Description | Journal: Journal of Thoracic and Cardiovascular Surgery Although the incidence of lung cancer has decreased over the past decades, disparities in survival and treatment modalities have been observed for black and white patients with early stage non-small cell lung cancer (NSCLC), despite the fact that surgical resection has been established as the standard of care. Possible contributors to these disparities are stage at diagnosis, comorbidities, socio-economic factors, and patient preference. This study examines racial disparities in treatment, adjusting for clinicodemographic factors. The Surveillance, Epidemiology, and End Results (SEER)-Medicare dataset was queried to identify patients diagnosed with primary stage I NSCLC between 1992-2009. Multivariable logistic regressions were performed to assess the association between race and treatment modalities within 1 year of diagnosis, adjusted for clinical and demographic factors. Adjusted Cox proportional hazards models were performed to evaluate disparities in survival, accounting for mode of treatment. We identified 22,724 patients; 21,230 (93.4%) white and 1,494 (6.6%) black. Black patients were less likely to receive treatment (Odds Ratio $(OR)_{adj}$: 0.62, 95% Confidence Interval (CI): 0.53-0.73) and less likely to receive surgery only when treated $(OR_{adj}$: 0.70, 95% CI: 0.61-0.79). Although univariate survival for black patients was worse, when accounting for treatment mode, there was no difference in survival (Hazard Ratio $(HR)_{adj}$: 0.97, 95% CI: 0.90-1.04 for all patients, $HR_{adj}$: 0.98, 95% CI: 0.90-1.06 for treated patients). Treatment disparities persist, even when adjusting for clinical and demographic factors. However, when black patients receive similar treatment, survival is comparable to white patients. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433143/pdf http://www.jtcvs.org/article/S0022522318332586/pdf |
| ISSN | 00225223 |
| e-ISSN | 1097685X |
| DOI | 10.1016/j.jtcvs.2018.11.108 |
| Journal | Journal of Thoracic and Cardiovascular Surgery |
| Issue Number | 4 |
| Volume Number | 157 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2019-04-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Thoracic and Cardiovascular Surgery Ethnic Studies |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine Surgery Cardiology and Cardiovascular Medicine |
