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Biofilms and Cyclic di-GMP (c-di-GMP) Signaling: Lessons from Pseudomonas aeruginosa and Other Bacteria
| Content Provider | Scilit |
|---|---|
| Author | Valentini, Martina Filloux, Alain |
| Copyright Year | 2016 |
| Description | Journal: Journal of Biological Chemistry The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that regulates many bacterial behaviors and is of key importance for driving the lifestyle switch between motile loner cells and biofilm formers. This review provides an up-to-date compendium of c-di-GMP pathways connected to biofilm formation, biofilm-associated motilities, and other functionalities in the ubiquitous and opportunistic human pathogen Pseudomonas aeruginosa. This bacterium is frequently adopted as a model organism to study bacterial biofilm formation. Importantly, its versatility and adaptation capabilities are linked with a broad range of complex regulatory networks, including a large set of genes involved in c-di-GMP biosynthesis, degradation, and transmission. |
| Related Links | http://www.jbc.org/content/291/24/12547.full.pdf https://core.ac.uk/download/pdf/77011915.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933438/pdf http://www.jbc.org/article/S0021925820408981/pdf |
| Ending Page | 12555 |
| Page Count | 9 |
| Starting Page | 12547 |
| ISSN | 00219258 |
| e-ISSN | 1083351X |
| DOI | 10.1074/jbc.r115.711507 |
| Journal | Journal of Biological Chemistry |
| Issue Number | 24 |
| Volume Number | 291 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2016-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Biological Chemistry Antibiotic Resistance Cyclic Di-gmp (c-di-gmp) Pseudomonas Aeruginosa (p. Aeruginosa) |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Biochemistry Molecular Biology |
