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CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES
| Content Provider | Scilit |
|---|---|
| Author | Katz, David H. Dorf, Martin E. Benacerraf, Baruj |
| Copyright Year | 1974 |
| Description | In our initial studies on the question of histocompatibility requirements in T-B-cell interactions, we found that no cooperation occurred with mixtures of T and B cells from BALB/c (H-2d) and A/J (H-2a) donors, respectively (1). These particular strains are identical for genes in the S and D regions of the H-2 complex but possess major differences at the K-end. Many differences are known to exist in the I region as well. Thus, these early data indicated that gene identities only at the D-end are insufficient to permit optimal cooperative interactions to occur under these conditions. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139692/pdf |
| Ending Page | 295 |
| Page Count | 6 |
| Starting Page | 290 |
| DOI | 10.1084/jem.140.1.290 |
| Journal | The Journal of experimental medicine |
| Issue Number | 1 |
| Volume Number | 140 |
| Language | English |
| Publisher | Rockefeller University Press |
| Publisher Date | 1974-07-01 |
| Access Restriction | Open |
| Subject Keyword | Immunology Tissue Culture Histocompatibility Genes Immunoglobulins Journal: The Journal of experimental medicine (Vol- 140, Issue- 1) |
| Content Type | Text |