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Bridging long gap peripheral nerve injury using skeletal muscle-derived multipotent stem cells
| Content Provider | Scilit |
|---|---|
| Author | Tamaki, Tetsuro |
| Copyright Year | 2014 |
| Abstract | Long gap peripheral nerve injuries usually reulting in life-changing problems for patients. Skeletal muscle derived-multipotent stem cells (Sk-MSCs) can differentiate into Schwann and perineurial/endoneurial cells, vascular relating pericytes, and endothelial and smooth muscle cells in the damaged peripheral nerve niche. Application of the Sk-MSCs in the bridging conduit for repairing long nerve gap injury resulted favorable axonal regeneration, which showing superior effects than gold standard therapy--healthy nerve autograft. This means that it does not need to sacrifice of healthy nerves or loss of related functions for repairing peripheral nerve injury. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160861/pdf |
| Ending Page | 1336 |
| Page Count | 4 |
| Starting Page | 1333 |
| File Format | XHTML |
| ISSN | 16735374 |
| DOI | 10.4103/1673-5374.137582 |
| Journal | Neural Regeneration Research |
| Issue Number | 14 |
| Volume Number | 9 |
| Language | English |
| Publisher | Medknow |
| Access Restriction | Open |
| Subject Keyword | Cell Tissue Engineering Schwann Cells Blood Vessel Formation Cytokine Endoneurium Paracrine Effect Perineurium Peripheral Nerve Support Cells Neural Regeneration Research, Volume 9, Issue 14 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Developmental Neuroscience |
