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Colorimetric Determination of Phenylephrine hydrochloride Drug by Diazotization Reaction
| Content Provider | Scilit |
|---|---|
| Author | Alteemi, Hajir S. Kadim, Kassim H. |
| Copyright Year | 2020 |
| Description | Journal: Journal of Physics: Conference Series By diazotization coupling reaction is one of the most frequently employed technique in pharmaceutical analysis. It involves measuring the amount of ultraviolet or visible radiation absorbed by a substance in solution as a method for estimation drug of Phenylephrine hydrochloride by reliant on azo-coupling reaction between (PHE)HCl and Clonazepam as a reagent. To reach to the aim of obtaining the colored product with a maximum absorbance 466nm. The linearity range for Phenylephrine hydrochloride was (0.5_9μg\ml) while the detections limit 0.006 and quantification limit 0.02μg\ml The Molar Absorptivity 2.5457 $×10^{4}$L/mol.cm with Sandal’s sensitivity 0.01μg\cm2. Eventually these methods were successfully completed to determination of PHE.HCl in pure and commercial form. |
| Related Links | https://iopscience.iop.org/article/10.1088/1742-6596/1664/1/012097/pdf |
| ISSN | 17426588 |
| e-ISSN | 17426596 |
| DOI | 10.1088/1742-6596/1664/1/012097 |
| Journal | Journal of Physics: Conference Series |
| Issue Number | 1 |
| Volume Number | 1664 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2020-11-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Physics: Conference Series Analytical Chemistry Phenylephrine Hydrochloride Coupling Reaction Reaction By Diazotization |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physics and Astronomy |
