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The Bergen Blood Pressure Study: Ambulatory Blood Pressure in Subjects with an Accurately Defined Family History of Hypertension or Normotension
| Content Provider | Scilit |
|---|---|
| Author | Mo, Rune Lund-Johansen, Per Omvik, Per |
| Copyright Year | 1993 |
| Description | Journal: Blood Pressure 24-hour ambulatory blood pressure (BP) was monitored by non-invasive methods in 42 offspring of hypertensive families (age [mean (SD1)] 40(7) years) and 38 offspring of normotensive families (age 33(6) years). The family history was defined according to parental BP data from two surveys conducted 27 years apart. Casual BP was 137(17)/84(12) mmHg in offspring of hypertensive families and 117(9)/69(6) mmHg in offspring of normotensive families (difference: p < 0.001). Average 24-h BP was 123(10)/74(6) mmHg and 113(8)/65(5) mmHg, respectively (difference: p < 0.001). The systolic and diastolic BP difference of approximately 10 mmHg was observed between the groups throughout the monitoring period. Hypertension--defined according to a recent meta-analysis as an average 24-h BP > or = 139/87 mmHg--was found in 6 offspring of hypertensive families and in no offspring of normotensive families (p < 0.05). The 24-h systolic and diastolic BP load--the percentage of readings above 140/90 mmHg (day-time) and 120/80 mmHg (night-time)--was higher in offspring of hypertensive than normotensive families (27%/17% vs. 7%4%; p < 0.001). After adjustment for intrafamilial covariation, age, and other possibly confounding variables, the differences between the groups remained. The present findings suggest that BP in subjects with a family history of hypertension is elevated on a permanent basis, and not only when it is measured in the doctor's office. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/08037059309077551 |
| Ending Page | 204 |
| Page Count | 8 |
| Starting Page | 197 |
| ISSN | 08037051 |
| e-ISSN | 16511999 |
| DOI | 10.3109/08037059309077551 |
| Journal | Blood Pressure |
| Issue Number | 3 |
| Volume Number | 2 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1993-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Blood Pressure Peripheral Vascular Disease Blood Pressure Normotensive Family History Hypertensive Families |
| Content Type | Text |
| Subject | Internal Medicine Cardiology and Cardiovascular Medicine |