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Proteomic responses of skeletal and cardiac muscle to exercise

Content Provider	Scilit
Author	Burniston, Jatin G. Hoffman, Eric P.
Copyright Year	2011
Description	Journal: Expert Review of Proteomics Regular exercise is effective in the prevention of chronic diseases and confers a lower risk of death in individuals displaying risk factors such as hypertension and dyslipidemia. Thus, knowledge of the molecular responses to exercise provides a valuable contrast for interpreting investigations of disease and can highlight novel therapeutic targets. While exercise is an everyday experience and can be conceptualized in simple terms, it is also a complex physiological phenomenon and investigation of exercise responses requires sophisticated analytical techniques and careful standardization of the exercise stimulus. Proteomic investigation of exercise is in its infancy but the ability to link changes in function with comprehensive changes in protein expression and post-translational modification holds great promise for advancing physiology. This article highlights recent pioneering work investigating the effects of exercise in skeletal and cardiac muscle that has uncovered novel mechanisms underlying the benefits of physical activity.
Related Links	http://europepmc.org/articles/pmc4948674?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948674/pdf
Ending Page	377
Page Count	17
Starting Page	361
ISSN	14789450
e-ISSN	17448387
DOI	10.1586/epr.11.17
Journal	Expert Review of Proteomics
Issue Number	3
Volume Number	8
Language	English
Publisher	Informa UK Limited
Publisher Date	2011-06-01
Access Restriction	Open
Subject Keyword	Journal: Expert Review of Proteomics Skeletal Muscle Proteomics Cardiac Muscle Proteomics Exercise Training Cardioprotection 2-d Gel Electrophoresis Mass Spectrometry Post-translational Modification Heat Shock Proteins Atp Synthase Beta.
Content Type	Text
Subject	Biochemistry Molecular Biology

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