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N-Ethyl-N-Nitrosourea Mutagenesis: Functional Analysis of the Mouse Nervous System and Behavior
| Content Provider | Scilit |
|---|---|
| Author | Kanes, Stephen J. Leach, Gillian R. Bucan, Maja |
| Copyright Year | 2001 |
| Description | As the human and mouse genome projects approach completion, the challenge will be to determine the function of the many genes being discovered. Often, newly identified genes can be assigned a function based on their homology with known genes, but, to fully understand their function, one must study the phenotypic consequences of mutations in these genes. This effort, often called functional genomics, has the potential to revolutionize our understanding of genes that affect behavior and perhaps provide critical clues about the biological underpinnings of neurological and psychiatric disorders. The mouse represents an important model organism for these studies; a variety of mutations can be engineered in individual genes and progeny of mutagenized mice can be examined to identify genetic variants with specific behavioral anomalies. Book Name: Methods in Genomic Neuroscience |
| Related Links | https://content.taylorfrancis.com/books/download?dac=C2010-0-33430-9&isbn=9780429126192&doi=10.1201/9781420038477-8&format=pdf |
| Ending Page | 140 |
| Page Count | 28 |
| Starting Page | 113 |
| DOI | 10.1201/9781420038477-8 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2001-09-26 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Methods in Genomic Neuroscience Functional Genomics Provide Critical Phenotypic Consequences Critical Clues |
| Content Type | Text |
| Resource Type | Chapter |
