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Research progress of circular RNAs in lung cancer
| Content Provider | Scilit |
|---|---|
| Author | Ma, Yi Zhang, Xin Wang, Yi-Zhi Tian, Hao Xu, Shun |
| Copyright Year | 2018 |
| Description | Journal: Cancer Biology & Therapy Lung cancer is one of the most common cancers and the leading cause of cancer-related death worldwide. Despite encouraging results achieved with targeted therapy in recent years, the early diagnosis and treatment of lung cancer remains a major problem. Circular RNA (circRNA), a type of RNA with covalently closed continuous loop structures, has structural stability and certain tissue specificity. Recent studies have found that circRNAs have an important role in tumor development and are expected to be revealed as new targets for tumor prediction and treatment. Research on the biological functions and regulation mechanisms of circRNAs in lung cancer is in its infancy but is gathering momentum. In this review, we discuss the properties, biogenesis, biological function, and research progress of circRNAs in lung cancer to provide a theoretical foundation and new directions for studies on circRNAs in lung cancer. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.1080/15384047.2018.1523848?needAccess=true https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343721/pdf |
| Ending Page | 129 |
| Page Count | 7 |
| Starting Page | 123 |
| ISSN | 15384047 |
| e-ISSN | 15558576 |
| DOI | 10.1080/15384047.2018.1523848 |
| Journal | Cancer Biology & Therapy |
| Issue Number | 2 |
| Volume Number | 20 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2019-02-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Cancer Biology & Therapy Back-splicing Circular Rna Microrna Sponge Therapeutic Target |
| Content Type | Text |
| Subject | Cancer Research Pharmacology Molecular Medicine Oncology |
