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Structure and Reactivity of Organozinc Reagents
| Content Provider | Scilit |
|---|---|
| Author | Erdik, Ender |
| Copyright Year | 2020 |
| Description | Organozinc reagents form one of the first classes in the main group of organometallic compounds. A number of methods are available for efficient and rapid preparation of organozinc reagents, and they react with various organic electrophiles in high yields. Organozinc reagents also show excellent functional group tolerance, and reactions of the functional group-bearing organozinc cuprates prepared by transmetallation of organozinc reagents prior to the reaction allow construction of polyfunctional molecules without the need to use protection-deprotection or functional group interconversion methodologies. Especially cross-coupling and conjugate-addition reactions of organozinc reagents can also be catalyzed by transition metal salts, and catalyzed reactions have advantages over the conventional ones for the control of the regio- and stereoselectivity. In addition, the use of electrophilic or nucleophilic chiral catalysts in the reactions of organozinc reagents with carbonyl substrates, which is one of the most fundamental operations in organic synthesis, leads to highly stereoselective additions. There has been an increasingly large amount of research devoted to organozinc chemistry in recent years. Book Name: ORGANOZINC REAGENTS in ORGANIC SYNTHESIS |
| Related Links | https://content.taylorfrancis.com/books/download?dac=C2006-0-18222-X&isbn=9781003069256&doi=10.1201/9781003069256-1&format=pdf |
| DOI | 10.1201/9781003069256-1 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2020-09-23 |
| Access Restriction | Open |
| Subject Keyword | Book Name: ORGANOZINC REAGENTS in ORGANIC SYNTHESIS Organic Chemistry Functional Group Stereoselectivity Organozinc Reagents Electrophilic |
| Content Type | Text |
| Resource Type | Chapter |
