NDLI: Sensorineural Hearing Loss in Antigen-induced Otitis Media

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Sensorineural Hearing Loss in Antigen-induced Otitis Media

Content Provider	Scilit
Author	Morizono, Tetsuo Hamaguchi, Yukiyoshi Juhn, Steven K.
Copyright Year	1988
Description	Journal: Acta Oto-Laryngologica Chinchillas were sensitized with human serum albumin (HSA). When circulating antibody-titers were sufficiently elevated as to induce local inflammation, 1 ml of HSA (50, 5, 0.5 mg/ml) was instilled into the left middle ear cavity from the superior bulla. HSA containing a steroid agent was instilled into the right ear. Non-sensitized animals were used as control. In the sensitized animals, a significant hearing loss occurred at higher frequencies. The loss was dose-related. Less severe hearing loss was found following steroid treatment. We conclude that sensorineural hearing loss can occur in antigen-induced otitis media.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/00016488809138886
Ending Page	72
Page Count	6
Starting Page	67
ISSN	00016489
e-ISSN	16512251
DOI	10.3109/00016488809138886
Journal	Acta Oto-Laryngologica
Issue Number	sup457
Volume Number	105
Language	English
Publisher	Informa UK Limited
Publisher Date	1988-01-01
Access Restriction	Open
Subject Keyword	Journal: Acta Oto-Laryngologica Otorhinolaryngology Hearing Loss Sensorineural Hearing Sensitized Animals Loss Occurred Antigen Induced Induced Otitis
Content Type	Text
Subject	Otorhinolaryngology

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