NDLI: Light-Scattering Method in Particle Size Analysis of Parenteral Emulsions

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Light-Scattering Method in Particle Size Analysis of Parenteral Emulsions

Content Provider	Scilit
Author	Tian, Youqin Chiu, Luk
Copyright Year	1998
Description	Journal: Drug Development and Industrial Pharmacy The use of a light-scattering particle size distribution analyzer has been shown to be a convenient method for characterizing the particle size distribution of parenteral emulsions. However, the concentrations of the samples used were found to have a major impact on the particle size distribution results, particularly for samples with a mean particle size smaller than 0.2 micron. An increase in sample concentration caused a shift to smaller particle sizes as a result of multiple scattering. The blue-light (tungsten lamp) intensity, instead of the He-Ne laser integrity, should be used to control sample concentration within the optimal range for measurement.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/03639049809085620
Ending Page	280
Page Count	6
Starting Page	275
ISSN	03639045
e-ISSN	15205762
DOI	10.3109/03639049809085620
Journal	Drug Development and Industrial Pharmacy
Issue Number	3
Volume Number	24
Language	English
Publisher	Informa UK Limited
Publisher Date	1998-01-01
Access Restriction	Open
Subject Keyword	Journal: Drug Development and Industrial Pharmacy Pharmacology and Pharmacy Light Scattering Parenteral Emulsions Particle Size
Content Type	Text
Subject	Organic Chemistry Drug Discovery Pharmacology Pharmaceutical Science

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