NDLI: The intimate relationship between gut microbiota and cancer immunotherapy

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The intimate relationship between gut microbiota and cancer immunotherapy

Content Provider	Scilit
Author	Elkrief, Arielle Derosa, Lisa Zitvogel, Laurence Kroemer, Guido Routy, Bertrand
Copyright Year	2018
Description	Journal: Gut Microbes Immunotherapy is widely used to treat a large variety of malignancies and has revolutionized the therapeutic approach to cancer. Major efforts are ongoing to identify biomarkers that predict response to immunotherapy as well as new strategies to improve ICI efficacy and clinical outcomes. Studies have shown that the gut microbiome determines the extent to which ICIs may invigorate the anticancer immune response. Here, the authors review recent studies that have described the effects of the gut microbiota on the efficacy of CTLA-4 and PD-1 inhibitors and outline potential future clinical directions of these findings.
Related Links	https://www.tandfonline.com/doi/pdf/10.1080/19490976.2018.1527167?needAccess=true https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546322/pdf
Ending Page	428
Page Count	5
Starting Page	424
ISSN	19490976
e-ISSN	19490984
DOI	10.1080/19490976.2018.1527167
Journal	Gut Microbes
Issue Number	3
Volume Number	10
Language	English
Publisher	Informa UK Limited
Publisher Date	2019-05-04
Access Restriction	Open
Subject Keyword	Journal: Gut Microbes Research and Experimental Medicine Gut Microbiota Immunotherapy Fecal Transplantation Profiling Gut Microbiome Host Pathogen Interactions
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Gastroenterology Microbiology Microbiology (medical)

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