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Benzodiazepine Withdrawal Syndrome: A Literature Review and Evaluation
| Content Provider | Scilit |
|---|---|
| Author | Mackinnon, Glenda L. Parker, William A. |
| Copyright Year | 1982 |
| Description | Journal: The American journal of drug and alcohol abuse The capacity of the benzodiazepine drugs to produce dependence and addiction has been associated with what has recently been recognized as a benzodiazepine withdrawal syndrome. Abrupt discontinuation of benzodiazepine treatment may show a spectrum of symptoms similar to those observed from withdrawal of alcohol or barbiturates. Such reactions have been reported with and are reviewed for the following drugs: chlordiazepoxide, diazepam, oxazepam, lorazepam, nitrazepam, temazepam, and clobazam. Generally, the higher the dose and the longer the benzodiazepine is taken, the greater the risk of developing withdrawal symptoms. However, withdrawal symptoms may occur in patients receiving recommended doses and/or short-term therapy. Although most withdrawal reactions have been reported with the long-acting benzodiazepines having psychoactive metabolites, reactions may also occur with the short-acting agents. In contrast, rebound insomnia occurs with greater frequency and severity with the short-acting agents. Benzodiazepine therapy should be stopped as early as possible, with tapering after moderate dose and/or prolonged use therapy. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/00952998209002608 |
| Ending Page | 33 |
| Page Count | 15 |
| Starting Page | 19 |
| ISSN | 00952990 |
| e-ISSN | 10979891 |
| DOI | 10.3109/00952998209002608 |
| Journal | The American journal of drug and alcohol abuse |
| Issue Number | 1 |
| Volume Number | 9 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1982-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: The American journal of drug and alcohol abuse Clinical Psychology Benzodiazepine Withdrawal Symptoms Withdrawal Syndrome Acting Agents |
| Content Type | Text |
| Subject | Clinical Psychology Psychiatry and Mental Health |
