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Effect of antenatal tocolysis on neonatal outcomes
| Content Provider | Scilit |
|---|---|
| Author | Klauser, Chad K. Briery, Christian M. Keiser, Sharon D. Martin, Rick W. Kosek, Mary A. Morrison, John C. |
| Copyright Year | 2012 |
| Description | Journal: The Journal of Maternal-Fetal & Neonatal Medicine Objective: Detail adverse neonatal effects in pregnancies treated with indomethacin (I), magnesium sulfate (M) or nifedipine (N). Methods: Women in acute preterm labor with cervical dilatation 1–6 cm were randomized to receive one of three first-line tocolytic drugs. Results: There were 317 neonates (I = 103, M = 95, N = 119) whose mothers were treated with tocolytic therapy. There was no difference in gestational age at randomization (average 28.6 weeks' gestation) or at delivery (31.6 weeks' gestation, p = 0.551), birth weight (p = 0.871) or ventilator days (p = 0.089) between the three groups. Neonatal morbidity was not different between the three groups; respiratory distress syndrome (p = 0.086), patent ductus arteriosus (p = 0.592), sepsis (p = 0.590), necrotizing enterocolitis (p = 0.770), intraventricular hemorrhage (p = 0.669) and periventricular leukomalacia (p = 0.124). Conclusions: There were no statistically significant differences between the three tocolytics as far as composite neonatal morbidity or mortality was concerned. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.3109/14767058.2012.714819 |
| Ending Page | 2781 |
| Page Count | 4 |
| Starting Page | 2778 |
| ISSN | 14767058 |
| e-ISSN | 14764954 |
| DOI | 10.3109/14767058.2012.714819 |
| Journal | The Journal of Maternal-Fetal & Neonatal Medicine |
| Issue Number | 12 |
| Volume Number | 25 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2012-08-20 |
| Access Restriction | Open |
| Subject Keyword | Journal: The Journal of Maternal-Fetal & Neonatal Medicine Pediatrics and Child Health Neonatal Morbidity Preterm Labor Treatment |
| Content Type | Text |
| Subject | Pediatrics, Perinatology and Child Health Obstetrics and Gynecology |
