NDLI: Development and Evaluation of Micropelleted Sustained-Release Suppositories of Terbutaline Sulfate

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Development and Evaluation of Micropelleted Sustained-Release Suppositories of Terbutaline Sulfate

Content Provider	Scilit
Author	Arra, G. S. Biswanath, S. A. Krishna, D. R. Arutla, S. Bandyopadhyay, A. K.
Copyright Year	1997
Description	Journal: Drug Development and Industrial Pharmacy Terbutaline sulfate (TS), a β2 agonist, was fabricated in the form of micropelleted sustained-release suppositories. Micropellets of TS using Eudragit RS100 were prepared by emulsification-solvent evaporation technique and were incorporated into suppositories (PEG 4000 as base) by fusion method. Physical, in vitro and in vivo evaluations were carried out for both conventional (PEG 4000 base) and micropelleted sustained-release suppositories and were compared. Micropellets were scanned using electron microscopy to see the surface structure before and after the in vitro dissolution.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/03639049709146163
Ending Page	1237
Page Count	5
Starting Page	1233
ISSN	03639045
e-ISSN	15205762
DOI	10.3109/03639049709146163
Journal	Drug Development and Industrial Pharmacy
Issue Number	12
Volume Number	23
Language	English
Publisher	Informa UK Limited
Publisher Date	1997-01-01
Access Restriction	Open
Subject Keyword	Journal: Drug Development and Industrial Pharmacy Integrative and Complementary Medicine Sustained Release Suppositories Micropelleted Sustained Release
Content Type	Text
Subject	Organic Chemistry Drug Discovery Pharmacology Pharmaceutical Science

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