NDLI: Role of Collagen Fibrils in Calcification

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Role of Collagen Fibrils in Calcification

Content Provider	Scilit
Author	Bonucci, E.
Copyright Year	2020
Description	Collagen is the major constituent of the organic matrix of bone and is present in other calcifying tissues. Consequently, although calcification can occur in noncollagenous matrices, as for instance enamel matrix, the role of collagen fibrils in inducing and regulating the calcification process is considered of primary importance. On the other hand, collagen is one of the most abundant proteins in noncalcifying mammalian tissues, being present at different concentrations and in different forms in all mesenchymal tissues. This means that collagen by itself is not determinant for the induction of calcification, this process depending on a complex equilibrium of cellular functions, protein syntheses, molecular interactions, enzymatic activities, electrolyte concentrations, and removal of inhibitors. Thus, it is not completely justified to examine the role of collagen fibrils in calcification separately from that which other matrix components can have. However, for simplification and because most of these components are considered in other parts of this volume, calcification of collagen fibrils will be considered mainly as a local process depending primarily on the structure and composition of the fibrils themselves. Book Name: Calcification in Biological Systems
Related Links	https://content.taylorfrancis.com/books/download?dac=C2006-0-01291-8&isbn=9781003068396&doi=10.1201/9781003068396-3&format=pdf
Ending Page	39
Page Count	21
Starting Page	19
DOI	10.1201/9781003068396-3
Language	English
Publisher	Informa UK Limited
Publisher Date	2020-07-24
Access Restriction	Open
Subject Keyword	Book Name: Calcification in Biological Systems Dentistry and Oral Surgery Role of Collagen Fibrils Fibrils in Calcification
Content Type	Text
Resource Type	Chapter

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